Exploring the immune interactions among Oncomelania hupensis and Schistosoma japonicum, with a cross-comparison of immunological investigation progress in other intermediate host snails Hongyu Li
Mortality might be prevented by administration of neutralizing MIF-distinct antibodies66 (Box one). Experiments completed in Mif-deficient mice verified that a lack of Mif is affiliated with amplified resistance to Gram-positive shock attributable to staphylococcal enterotoxin B8 (Box 1). MIF can be released by cells of entire blood stimulated with warmth-killed Streptococcus pneumoniae, and MIF-specific antibody cuts down cytokine output and increases survival in a very mouse product of S. pneumoniae-induced pneumonia (T.C. et al., unpublished observations). along with the observations acquired in experimental models of endotoxaemia and Gram-unfavorable sepsis, these facts point out that MIF has a significant function from the pathogenesis of bacterial bacterial infections.
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